ARDS: hidden perils of an overburdened diagnosis

ARDS: hidden perils of an overburdened diagnosis

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Abstract A diagnosis of ARDS serves as a pretext for several perilous clinical practices.Clinical trials demonstrated that tidal volume 12 ml/kg increases patient mortality, but 6 ml/kg has not proven superior to 11 ml/kg or anything in between.Present guidelines recommend 4 ml/kg, which foments severe air hunger, leading to prescription of hazardous (yet ineffective) sedatives, narcotics here and paralytic agents.

Inappropriate lowering of tidal volume also fosters double triggering, which promotes alveolar overdistention and lung injury.Successive panels have devoted considerable energy to developing a more precise definition of ARDS to homogenize the recruitment of patients into clinical trials.Each of three pillars of the prevailing Berlin definition is extremely flimsy and the source of confusion and unscientific practices.

For doctors at the bedside, none of the revisions have enhanced patient care over that using the original 1967 description of Ashbaugh and colleagues.Bedside doctors are better advised to diagnose ARDS on the basis of pattern recognition and instead concentrate their vigilance on resolving the numerous hidden dangers quadruple topical ointment for dogs that follow inevitably once a diagnosis has been made.